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John Hwa Lee Selected Research

E coli heat-labile enterotoxin

7/2015Comparison of a live attenuated Salmonella Enteritidis vaccine candidate secreting Escherichia coli heat-labile enterotoxin B subunit with a commercial vaccine for efficacy of protection against internal egg contamination by Salmonella in hens.
1/2014Construction of a recombinant-attenuated Salmonella Enteritidis strain secreting Escherichia coli heat-labile enterotoxin B subunit protein and its immunogenicity and protection efficacy against salmonellosis in chickens.
9/2013Enhanced protective immune responses against Salmonella Enteritidis infection by Salmonella secreting an Escherichia coli heat-labile enterotoxin B subunit protein.
5/2013Oral immunization with an attenuated Salmonella Gallinarum mutant as a fowl typhoid vaccine with a live adjuvant strain secreting the B subunit of Escherichia coli heat-labile enterotoxin.
12/2012Attenuated Salmonella Gallinarum secreting an Escherichia coli heat-labile enterotoxin B subunit protein as an adjuvant for oral vaccination against fowl typhoid.

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John Hwa Lee Research Topics

Disease

48Infections
01/2022 - 01/2006
21Typhoid Fever (Typhoid)
01/2022 - 09/2010
17Salmonella Infections (Salmonellosis)
01/2022 - 07/2010
14Brucellosis (Malta Fever)
09/2021 - 06/2017
10Human Influenza (Influenza)
10/2021 - 01/2017
7Diarrhea
01/2015 - 07/2010
5Influenza in Birds (Avian Flu)
03/2020 - 01/2017
4Neoplasms (Cancer)
06/2022 - 07/2015
4Communicable Diseases (Infectious Diseases)
01/2022 - 01/2015
4Edema (Dropsy)
06/2018 - 05/2006
3Neuroinflammatory Diseases
01/2016 - 11/2015
2Pneumonia (Pneumonitis)
01/2022 - 10/2020
2Virus Diseases (Viral Diseases)
01/2017 - 07/2010
2Pleuropneumonia
01/2016 - 03/2014
2Atrophic Rhinitis (Ozena)
10/2014 - 09/2014
2Body Weight (Weight, Body)
05/2013 - 06/2011
1Breast Neoplasms (Breast Cancer)
06/2022
1Weight Loss (Weight Reduction)
01/2022
1COVID-19
01/2022
1Severe Acute Respiratory Syndrome
01/2022
1Marek Disease (Marek's Disease)
09/2021
1Tremor (Tremors)
01/2021
1Dengue (Dengue Fever)
01/2020
1Splenomegaly
10/2019
1Bronchitis
09/2018
1Orchitis
08/2017
1Autolysis
02/2017
1Porcine Reproductive and Respiratory Syndrome (PRRS)
11/2015

Drug/Important Bio-Agent (IBA)

63VaccinesIBA
01/2022 - 08/2007
21AntigensIBA
03/2021 - 06/2011
8Proteins (Proteins, Gene)FDA Link
03/2020 - 07/2010
7CytokinesIBA
06/2020 - 07/2010
5Interleukin-10 (Interleukin 10)IBA
09/2021 - 01/2016
5FlagellinIBA
07/2021 - 01/2017
5E coli heat-labile enterotoxinIBA
07/2015 - 12/2012
4Interleukin-6 (Interleukin 6)IBA
09/2021 - 01/2016
4Interleukin-12 (IL 12)IBA
05/2020 - 02/2017
4Inactivated VaccinesIBA
07/2018 - 08/2007
3O Antigens (O Antigen)IBA
01/2022 - 01/2018
3Subunit VaccinesIBA
06/2020 - 08/2007
3Salmonella VaccinesIBA
05/2019 - 07/2010
3Combined VaccinesIBA
10/2018 - 04/2013
3Protein Subunits (Protein Subunit)IBA
01/2014 - 12/2012
2mRNA VaccinesIBA
01/2022 - 01/2022
2Protease La (Endopeptidase La)IBA
01/2022 - 11/2020
2Arachidonic Acid (Vitamin F)IBA
03/2021 - 05/2006
2Sodium Bicarbonate (Baking Soda)FDA LinkGeneric
01/2021 - 01/2020
2Biological ProductsIBA
10/2020 - 01/2020
2Membrane Proteins (Integral Membrane Proteins)IBA
01/2020 - 09/2018
2Superoxide Dismutase-1IBA
01/2020 - 09/2018
2Hemagglutinins (Hemagglutinin)IBA
01/2020 - 06/2017
2DNA VaccinesIBA
01/2019 - 08/2017
2fluorescein thiocarbamylethylenediamine (FEDA)IBA
06/2018 - 07/2012
2Shiga Toxin (Shigella Toxin)IBA
02/2017 - 12/2016
2Virulence Factors (Pathogenicity Factors)IBA
01/2017 - 05/2013
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
12/2015 - 01/2006
2Antiviral Agents (Antivirals)IBA
11/2015 - 07/2010
2Immunoglobulin G (IgG)IBA
05/2013 - 06/2011
1Tryptophan (L-Tryptophan)FDA Link
06/2022
1Angiotensin-Converting Enzyme 2IBA
01/2022
1CatalaseIBA
01/2022
1Peroxidase (Myeloperoxidase)IBA
01/2022
1Green Fluorescent ProteinsIBA
09/2021
1Phosphates (Orthophosphate)IBA
09/2021
1Pharmaceutical PreparationsIBA
09/2021
1Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinIBA
09/2021
1lauric acid (dodecanoic acid)IBA
09/2021
1PhytochemicalsIBA
03/2021
1Phospholipases A2 (Phospholipase A2)IBA
03/2021
1Palmitic Acid (Hexadecanoic Acid)IBA
03/2021
1Fatty Acids (Saturated Fatty Acids)IBA
03/2021
1Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2021
1Magnesium Hydroxide (Brucite)FDA Link
01/2021
1LipidsIBA
01/2021
1Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
01/2021
1NitritesIBA
05/2020
1Linoleic Acid (Linoleate)IBA
05/2020
1ChitosanIBA
03/2020
1Messenger RNA (mRNA)IBA
03/2020
1Purinergic P1 Receptors (Adenosine Receptor)IBA
03/2020
1AntacidsIBA
01/2020
1Chemokine ReceptorsIBA
10/2019
1plerixaforFDA Link
10/2019
1PolyethyleneimineIBA
03/2019
1A-Form DNA (A-DNA)IBA
01/2019
1DNA (Deoxyribonucleic Acid)IBA
10/2018
16,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)IBA
09/2018
1proline racemaseIBA
09/2018
1LipopolysaccharidesIBA
08/2017
1Brucella VaccineIBA
06/2017
1Toll-Like Receptors (Toll-Like Receptor)IBA
03/2017
1Radiation-Protective Agents (Radiation Protectants)IBA
01/2017
1EmulsionsIBA
01/2017
1LigandsIBA
10/2016
1CC ChemokinesIBA
12/2015
1Attenuated VaccinesIBA
12/2015
1Transcription Factors (Transcription Factor)IBA
11/2015

Therapy/Procedure

4Therapeutics
06/2022 - 07/2015
2Oral Administration
01/2021 - 07/2010
1Intranasal Administration
03/2017